Major Shareholders

Auris Medical Holding AG
Amount Shares*Percentage Outstanding Shares*
Sofinnova Ventures Partners VIII, L.P.7,818,175**17.63%**
Thomas Meyer (Chairman & CEO, Auris Medical Holding AG)7,242,500**16.33%**
Sofinnova Capital VII FCPR5,384,45012.15%
Empery Asset Management, L.P. 2,500,000**5.64%**
*AS PER OUR ANNUAL REPORT ON FORM 20-F FILED ON MARCH 14, 2017
**COMMON SHARE OWNERSHIP ONLY, I.E. EXCLUDING WARRANTS AND OPTIONS